Ringer’s solution is also called Riger’s Solution, because Ringer’s solution contains sodium, potassium, calcium, and chloride in addition to sodium chloride. Because it was invented by the British physiologist “Ringer”, it is called Ringer’s solution. It is a kind of liquid that is relatively close to the internal environment of amphibians. It can be used to prolong the time of frog heart beating outside the body and maintain the physiological activity of other isolated amphibians tissues and organs.

Transportation and storage: transportation and storage at room temperature, use as soon as possible after opening!

This product is sterilized by 0.2μm filter!

Validity: 12 months

According to the specific requirements of the experiment, save or clean the isolated tissue.

Because Ringer’s solution contains calcium ions, precipitation is easy to occur. If a small amount of precipitation occurs, it can be used after heating to dissolve or filtering, and a large amount of precipitation should be discarded.

Ringer’s solution is a solution of several salts dissolved in water for the purpose of creating an isotonic solution relative to the body fluids of an animal. Ringer’s solution typically contains sodium chloride, potassium chloride, calcium chloride and sodium bicarbonate, with the last used to balance the pH. Other additions can include chemical fuel sources for cells, including ATP and dextrose, as well as antibiotics and antifungals.

Ringer’s solution is frequently used in in vitro experiments on organs or tissues, such as in vitro muscle testing. The precise mix of ions can vary depending upon the taxon, with different recipes for birds, mammals, freshwater fish, marine fish, etc.

Ringer’s solution is named after Sydney Ringer, who in 1882–1885 determined that a solution perfusing a frog’s heart must contain sodium, potassium and calcium salts in a definite proportion if the heart is to be kept beating for long.

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